FLEURY, MELISSA,GENDRON, ROLAND,HUGHES, ADAM D.,SCHMIDT, JANE
申请号:
CA2835281
公开号:
CA2835281A1
申请日:
2012.05.18
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula: (I) where R1, R2, R3, a, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.