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INHIBITEURS DE LA NÉPRILYSINE
专利权人:
Theravance Biopharma R&D IP; LLC
发明人:
HUGHES, Adam,FENSTER, Erik,FLEURY, Melissa,GENDRON, Roland,MORAN, Edmund J.
申请号:
MEP2017100
公开号:
ME02726B
申请日:
2012.11.01
申请国别(地区):
ME
年份:
2017
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
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