C14-hydroxyl esterified amino acid derivatives of triptolide, and preparation method and use thereof

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专利权人:

Hangzhou Weben Pharmaceuticals Inc

发明人:

Xu, Rongzhen,Jiang, Hongjian

申请号：

AU2015413013

公开号：

AU2015413013A1

申请日:

2015.10.29

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention belongs to the field of natural pharmaceuticals and pharmaceutical chemistry, and relates to novel esterified amino acid derivatives of triptolide of general formulae I and II or a pharmaceutically acceptable adduct, complex, salt and catabolites and metabolites thereof, and a method for preparing these compounds, a pharmaceutical composition containing the compound, and a use thereof in the preparation of drugs for against tumours, immunological diseases, or diseases associated with abnormal expressions of XPB or Pol II or oncogene c-myc.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/