Oliver Hill,Christian Gieffers,Meinolf Thiemann,Tim Schnyder
申请号：
US15795020
公开号：
US10793616B2
申请日:
2017.10.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are specific CD40 receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a CD40L-associated disease or disorder. The CD40 receptor agonist proteins provided herein comprise three soluble CD40L domains and an Fc fragment. The CD40 receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
