Christian Gieffers,Oliver Hill,Meinolf Thiemann,Tim Schnyder
申请号:
US15958180
公开号:
US10683338B2
申请日:
2018.04.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are specific TL1A receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TL1A-associated disease or disorder. The TL1A receptor agonist proteins provided herein comprise three soluble TL1A domains and an Fc fragment. The TL1A receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.