Gieffers, Christian,Hill, Oliver,Thiemann, Meinolf,Schnyder, Tim
申请号：
AU2016341402
公开号：
AU2016341402A1
申请日:
2016.10.24
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Provided herein are specific GITR receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a GITRL-associated disease or disorder. The GITR receptor agonist proteins provided herein comprise three soluble GITRL domains and an Fc fragment. The GITR receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
