STING-AKTIVIERENDER NANOIMPFSTOFF ZUR IMMUNTHERAPIE

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专利权人:

The Board of Regents of The University of Texas System

发明人:

GAO, Jinming,CHEN, Zhijian,LUO, Min,WANG, Zhaohui,WANG, Hua,CAI, Haocheng,HUANG, Gang,FU, Yang-Xin

申请号：

EP17760821

公开号：

EP3423044A4

申请日:

2017.03.02

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

In some aspects, the present disclosure provides vaccine compositions comprising an antigen and a diblock copolymer wherein the diblock copolymer is pH responsive. In some embodiments, these compositions activate the STING and/or the interferon receptor pathways. In some embodiments, the diblock copolymer hits a pKa from about 6 to about 7.5. Also provided herein are methods of treatment using these compositions to treat an infectious disease or cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/