Sting activating nanovaccine for immunotherapy

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专利权人:

The Board of Regents of The University of Texas System

发明人:

Gao, Jinming,Chen, Zhijian,Luo, Min,Wang, Zhaohui,Wang, Hua,Cai, Haocheng,Huang, Gang,Fu, Yang-Xin

申请号：

AU2017225769

公开号：

AU2017225769A1

申请日:

2017.03.02

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

In some aspects, the present disclosure provides vaccine compositions comprising an antigen and a diblock copolymer wherein the diblock copolymer is pH responsive. In some embodiments, these compositions activate the STING and/or the interferon receptor pathways. In some embodiments, the diblock copolymer has a pKa from about 6 to about 7.5. Also provided herein are methods of treatment using these compositions to treat an infectious disease or cancer.

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中国工程科技知识中心

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