The present invention relates to an extract of Angelica keiskei prepared by using enzymatic hydrolysis and a method for preparing the same and, more specifically, to an extract of Angelica keiskei which is prepared by hydrolyzing Angelica keiskei using an enzyme to increase the recovery rate in the extraction of insoluble substances. The extract of Angelica keiskei according to the present invention has a pharmacological activity, particularly, effects of suppressing sebum secretion, preventing and treating pimples, preventing hair loss, and promoting hair growth compared with the existing extraction method. Further, components that are hardly extracted by an existing extraction method can be extracted, thereby improving the extracting efficiency and providing now efficacy and functionality. That is, it was verified that the extract of Angelica keiskei alone prepared by the existing general hot-water extraction or organic solvent extraction method did not show effects of suppressing sebum secretion, preventing and treating pimples, preventing hair loss, and promoting hair growth, but the extract of Angelica keiskei prepared by the enzymatic hydrolysis method according to the present invention reduces activity of PPAR-gamma influencing the maturation of sebum cells, thereby suppressing sebum production and inhibiting 5-alpha-reductase. Thus, the extract of Angelica keiskei of the present invention can be used for an external application to the skin, which has effects of suppressing sebum secretion, preventing and treating pimples, preventing hair loss, and promoting hair growth.본 발명은 효소가수분해 방법을 이용하여 제조된 신선초 추출물 및 이의 제조방법에 관한 것으로서, 보다 상세하게는 효소를 이용하여 신선초를 가수분해함으로써 불용성 물질의 추출 회수율을 높이는 방법에 의하여 제조된 신선초 추출물에 관한 것이다.본 발명에 따른 신선초 추출물은 기존에 비해 약리활성, 특히 피지분비 억제 효과, 여드름 예방 및 치료효과, 탈모 방지 및 육모 효과가 있다. 더욱이 기존의 추출법으로 잘 추출되지 않는 성분이 추출됨으로써 추출 효율을 높이게 되었을 뿐만 아니라, 새로운 효능과 기능성을 나타내게 된다. 즉, 기존의 통상적인 열수 추출 또는 유기용매 추출 방법에 따른 신선초의 단독 추출물이 피지분비 억제 효과, 여드름 예방 및 치료효과, 탈모 방지 및 육모 효과에 아무런 효과를 보
