Syed M. Shah,Daniel Hassan,Fred Hassan,Patrick Corsino
申请号：
US15931135
公开号：
US20200268887A1
申请日:
2020.05.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A composition includes a pharmaceutical dosage form configured to disintegrate in oral saliva and maintain a pH of 4 or less within the saliva during the time the dosage form is dissolving therein, the dosage form including a therapeutically effective amount of melatonin in a polymer carrier matrix and a sufficient amount of acid to impart the pH to the saliva, the amount of disintegrant being sufficient to cause the dosage form to completely disintegrate in the saliva within ten minutes from contacting the saliva.
