Syed M. Shah,Daniel Hassan,Fred Hassan,Patrick Corsino
申请号：
US16676022
公开号：
US20200069803A1
申请日:
2019.11.06
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A composition includes an oral thin film pharmaceutical dosage form configured to disintegrate in saliva and maintain a pH of 4 or less within the saliva during the time the dosage form is dissolving therein. The dosage form includes a therapeutically effective amount of melatonin in a polymer carrier matrix and a sufficient amount of acid to impart the pH to the saliva. The dosage can completely disintegrate in the saliva within ten minutes from contacting the saliva.
