SHAH, Syed M.,HASSAN, Daniel,HASSAN, Fred,CORSINO, Patrick
申请号:
SG11201912172Y
公开号:
SG11201912172YA
申请日:
2018.06.15
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
A composition includes an oral thin film pharmaceutical dosage form configured to disintegrate in saliva and maintain a pH of 4 or less within the saliva during the time the dosage form is dissolving therein. The dosage form includes a therapeutically effective amount of melatonin in a polymer carrier matrix and a sufficient amount of acid to impart the pH to the saliva. The dosage can completely disintegrate in the saliva within ten minutes from contacting the saliva.