Jason Allan Wiles,Avinash S. Phadke,Milind Deshpande,Atul Agarwal,Dawei Chen,Venkat Rao Gadhachanda,Akihiro Hashimoto,Godwin Pais,Qiuping Wang,Xiangzhu Wang,William Greenlee
申请号：
US16867475
公开号：
US20200262818A1
申请日:
2020.05.05
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Compounds, methods of use, and processes for making inhibitors of complement Factor D are provided comprising Formula I, I″； and I′；″； or a pharmaceutically acceptable salt or composition thereof. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduces the excessive activation of complement.
