Jason Allan Wiles,Avinash S. Phadke,Milind Deshpande,Atul Agarwal,Dawei Chen,Venkat Rao Gadhachanda,Akihiro Hashimoto,Godwin Pais,Qiuping Wang,Xiangzhu Wang
申请号:
US15246049
公开号:
US20160361329A1
申请日:
2016.08.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compounds, methods of use, and processes for making inhibitors of complement factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof are provided. The inhibitors described herein target factor D and inhibit or regulate the complement cascade. The inhibitors of factor D described herein are capable of reducing the excessive activation of complement.