PARREN PAUL,GRAUS YVO,OPRINS JUDITH,WEERS MICHEL DE,VUGT MARTINE VAN,WINKEL JAN VAN DE
申请号：
NZ60005906
公开号：
NZ600059A
申请日:
2006.03.23
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed is an antibody binding to human CD38 encoded by: (i) human light chain and human heavy chain nucleic acids comprising nucleotide sequences in their variable regions as set forth in SEQ ID No:21 and SEQ ID No:26, respectively or (ii) human light chain and human heavy chain nucleic acids comprising nucleotide sequences in their variable regions, which are conservative sequence modifications of the sequences as set forth in (i). Further disclosed is an antibody binding to human CD38, comprising human light chain and human heavy variable regions, wherein the light chain variable region comprises a VL CDR1 having the sequence as set forth in SEQ ID No:23, a VL CDR2 having the sequence as set forth in SEQ ID No:24 and a VL CDR3 having the sequence as set forth in SEQ ID No:25, and the heavy chain variable region comprises a VH CDR1 having the sequence as set forth in SEQ ID No:28, a VH CDR2 having the sequence as set forth in SEQ ID No:29 and a VH CDR3 having the sequence as set forth in SEQ ID No:30.
