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Antibodies against cd38 for treatment of multiple myeloma
专利权人:
发明人:
WEERS MICHEL DE,GRAUS YVO,OPRINS JUDITH,PARREN PAUL PARREN,WINKEL JAN VAN DE,VUGT MARTINE VAN
申请号:
IN5497/CHENP/2014
公开号:
IN2014CN05497A
申请日:
2014.07.16
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
This invention relates to an antibody binding to human CD38 encoded by (i) human light chain and human heavy chain nucleic acids comprising nucleotide sequences in their variable regions as set forth in SEQ ID No:1 and SEQ ID No:6, respectively or (ii) human light chain and human heavy chain nucleic acids comprising nucleotide sequences in their variable regions, which are conservative sequence modifications of the sequences as set forth in (i). This invention also discloses nucleic acid, expression vectors, immunoconjugate, pharmaceutical composition kit etc., thereof.
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