HUMAN MATRIX SCIENCES, LLC;THE HOSPITAL FOR SICK CHILDREN
发明人:
Felipe JIMENEZ,Thomas MITTS,Aleksander HINEK
申请号:
US14523849
公开号:
US20150110755A1
申请日:
2014.10.25
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention describes therapeutic compositions comprising fibroblasts that have been stimulated to increase expression of extracellular matrix components or elastin, or to produce enhanced elastogenesis or the appearance thereof at a site of administration. The therapeutic fibroblast formulations can be prepared using a variety of elastogenic agents, including digests of mammalian elastin, chemically digested plant extracts comprising elastin-like peptides, and synthetic elastogenic peptides. The invention further comprises cosmetic and pharmaceutical treatment methods using the therapeutic fibroblast compositions of the invention.