The present invention relates heteroaryl fused phenyl derivatives, a preparation method thereof and pharmaceutical use thereof. Specifically, the present invention relates to a novel heteroaryl fused phenyl derivatives represented by the general formula (I), a preparation method thereof, pharmaceutical compositions containing the same and as a therapeutic agent, particularly the use as PAR-4 antagonist. The definition of each substituent of formula (I) is as defined in the specification.本發明涉及苯并雜芳基類衍生物、其製備方法及其在醫藥上的應用。具體而言,本發明涉及一種通式(I)所示的新的苯并雜芳基類衍生物、其製備方法及含有該衍生物的醫藥組成物以及其作為治療劑,特別是作為PAR-4拮抗劑的用途,其中通式(I)的各取代基與說明書中的定義相同。