CHANG, CHIH SHIANG,张志祥,張誌祥,GUH, JIH HWA,顾记华,顧記華,TENG, CHE MING,邓哲明,鄧哲明,PAN, SHIOW LIN,潘秀玲,潘秀玲,CHANG, WEI LING,张玮凌,張瑋凌,LIU, JU FANG,刘如芳,劉如芳,CHANG, KAI WEI,张凯惟,張凱惟,KUO, SHENG CHU,郭盛助,郭盛助
申请号：
TW098142356
公开号：
TWI458714B
申请日:
2009.12.10
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
Benzimidazole compounds of formula (I):wherein R1, R2, R3, R4, R5, X, Y, Z1, and Z2are defined herein. Also disclosed is a pharmaceutical composition comprising the benzimidazole compounds for use as an antiplatelet or antithrombotic agent, or for use in the treatment of cancer, or cardiovascular and cerebrovascular diseases.本發明係關於一種式(I)之苯并咪唑化合物:其中R1、R2、R3、R4、R5、X、Y、Z1、及Z2於本文中定義。亦揭示包含該等苯并咪唑化合物之醫藥組合物,其係作為抗血小板或抗血栓劑,或用於治療癌症、或是心血管及腦血管疾病。
