ROBERTS, EDWARD,GUERRERO, MIGUEL A.,URBANO, MARIANGELA,ROSEN, HUGH
申请号：
CA2882132
公开号：
CA2882132A1
申请日:
2013.08.16
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention provides novel ligands of Kappa (?) opioid receptors, such as can be used to modulate a Kappa opioid receptor. Methods of synthesis and methods of use are also provided. Compounds of the invention can be used therapeutically in the treatment of dissociative disorders or pain, or to provide neuroprotection, or to induce diuresis, or to modulate the immune system, or for treatment of one or more of an affective disorders comprising depression or stress/anxiety； an addictive disorder； alcoholism, epilepsy； a cognition deficiency； schizophrenia； Alzheimer's disease； or pain.
