PROCESS FOR MAKING M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

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专利权人:

发明人:

申请号：

EP16852356.1

公开号：

EP3356332A1

申请日:

2016.09.26

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

This invention provides novel processes for the preparation of compounds such as 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]-quinazolin-4(3H)-one, salts and derivatives thereof. The compounds synthesized by the processes of the invention are useful for treating Alzheimers disease and other diseases (e.g., cognitive impairment, schizophrenia, pain disorders, and sleep disorders) mediated by the muscarinic M1 receptor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/