A method of corneal implantation with cross-linking is disclosed herein. In one or more embodiments, the method includes the steps of: (i) forming a flap in a cornea of an eye so as to expose a stromal tissue of the cornea underlying the flap； (ii) pivoting the flap so as to expose the stromal tissue of the cornea underlying the flap； (iii) inserting an implant under the flap so as to overlie the stromal tissue of the cornea, wherein the implant is cross-linked so as to prevent an immune response to the implant and/or rejection of the implant by the patient； and (iv) covering the cross-linked implant with the flap, the cross-linked implant being surrounded entirely by the stromal tissue of the cornea.
