COMPOSITION PHARMACEUTIQUE SOLUBLE DANS L'EAU COMPRENANT AU MOINS UNE SUBSTANCE THÉRAPEUTIQUEMENT ACTIVE À CARACTÉRISTIQUES HYDROPHOBES ET AU MOINS UN COMPOSÉ SÉLECTIONNÉ PARMI LES SIALOGLYCOSPHINGOLIPIDES, LES GLYCOSPHINGOLIPIDES OU UN MÉLANGE DE SIALOGLYCOSPHINGOLIPIDES ET DE GLYCOSPHINGOLIPIDES
This invention discloses water soluble pharmaceutical compositions including at least one therapeutically active substance and at least one compound selected from the sialoglycosphingolipids, the glycosphingolipids or a mixture of sialoglicosphingolipids and glycosphingolipids, in which at least one of the therapeutically active substances is a drug with hydrophobic characteristics. In particular, sterile compositions for i.v. administration, composed of nano-glycosphingolipids micelles or modified glycosphingolipids, which can be coated with albumin in a noncovalent form and which allow transport and controlled release of highly hydrophobic molecules are disclosed.
