COMPOSITION PHARMACEUTIQUE SOLUBLE DANS L'EAU COMPRENANT AU MOINS UNE SUBSTANCE THÉRAPEUTIQUEMENT ACTIVE À CARACTÉRISTIQUES HYDROPHOBES ET AU MOINS UN COMPOSÉ SÉLECTIONNÉ PARMI LES SIALOGLYCOSPHINGOLIPIDES, LES GLYCOSPHINGOLIPIDES OU UN MÉLANGE DE SIALOGLYCOSPHINGOLIPIDES ET DE GLYCOSPHINGOLIPIDES
Consejo Nacional de Investigaciones Científicas y Tecnicas (CONICET);Centro de Excelencia en Productos y Procesos de Córdoba (CEPROCOR)
发明人:
申请号：
EP11755731.4
公开号：
EP2561861A1
申请日:
2011.03.14
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
This invention discloses water soluble pharmaceutical compositions including at least one therapeutically active substance and at least one compound selected from the sialoglycosphingolipids, the glycosphingolipids or a mixture of sialoglicosphingolipids and glycosphingolipids, in which at least one of the therapeutically active substances is a drug with hydrophobic characteristics. In particular, sterile compositions for i.v. administration, composed of nano-glycosphingolipids micelles or modified glycosphingolipids, which can be coated with albumin in a noncovalent form and which allow transport and controlled release of highly hydrophobic molecules are disclosed.
