SMITH, Peter G.,KEANEY, Gregg F.,WANG, John,ARAI, Kenzo,ZHENG, Guo Zhu,KIRA, Kazunobu,TIVITMAHAISOON, Parcharee,GEARHART, Nicholas C.,KOTAKE, Yoshihiko,NAGAO, Satoshi,MIYANO, Masayuki,MURAI, Norio,BUO
申请号:
MA39915
公开号:
MA39915B1
申请日:
2015.05.13
申请国别(地区):
MA
年份:
2019
代理人:
摘要:
The present invention provides novel pladienolide pyridine compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancer, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful.