Gregg F. Keaney,John Wang,Baudouin Gerard,Kenzo Arai,Xiang Liu,Guo Zhu Zheng,Kazunobu Kira,Parcharee Tivitmahaisoon,Sudeep Prajapati,Nicholas C. Gearhart,Yoshihiko Kotake,Satoshi Nagao,Regina Mikie Ka
申请号:
US14710687
公开号:
US09481669B2
申请日:
2015.05.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides novel pladienolide pyridine compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancer, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful.