КИНИ, Грегг Ф. (US),ВАН, Джон (US),ДЖЕРАРД, Бодуан (US),АРАИ, Кендзо (JP),ЛЮ, Сян (US),ЧЖЭН, Го Чжу (US),КИРА, Казунобу (JP),ТИВИТМАХАИСООН, Паршари (US),ПРАДЖАПАТИ, Судип (US),ГИРХАРТ, Николас С. (US
申请号:
RU2019124012
公开号:
RU2019124012A
申请日:
2015.05.13
申请国别(地区):
RU
年份:
2019
代理人:
摘要:
The present invention provides novel pladienolide pyridine compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancer, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful.