BUCHTA, RICHARD,HOULDEN, ROBERT JAMES,YE, ROSE,LARM, MARIA,LOUPENOK, LEON
申请号：
CA2611147
公开号：
CA2611147C
申请日:
2006.05.26
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
A pharmaceutical aerosol foam composition, comprising an effective amount of apharmaceutically active ingredient, wherein said pharmaceutically activeingredient is a vitamin or analogue thereof； an occlusive agent； an aqueoussolvent； an organic co-solvent； wherein the pharmaceutically active ingredientis insoluble in both water and the occlusive agent； and the occlusive agentbeing present in an amount sufficient to form an occlusive layer on the skin,in use. The pharmaceutically active ingredient can be selected from vitamin D3and vitamin A and/or their analogues such as calcipotriene, tretinoin,acitretin, etc. In a second embodiment, an oil-in-water emulsion having avitamin； an occlusive agent； an aqueous solvent； and an organic co-solvent,wherein the occlusive agent is present in an amount sufficient to foam anocclusive layer on the skin. The composition can be used to treatdermatological disorders such as psoriasis.
