Compositions and Methods for Modulating Immunodeficiency Virus Transcription

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专利权人:

Naoki Sakane

发明人:

Naoki Sakane,Melanie Ott

申请号：

US13252624

公开号：

US20120108500A1

申请日:

2011.10.04

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present disclosure provides methods of modulating immunodeficiency virus transcription, involving modulating enzymatic activity and/or levels of a lysine-specific demethylase-1 (LSD1) polypeptide and/or LSD1-mediated demethylation of methylated Tat. The present disclosure also provides method of identifying agents that modulate LSD1-mediated demethylation of a human immunodeficiency virus (HIV) Tat polypeptide.

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中国工程科技知识中心

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http://www.ckcest.cn/home/