INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
发明人:
Chae Ok Yun,Joung-Woo Choi
申请号:
US15458685
公开号:
US10357564B2
申请日:
2017.03.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to a composition for transduction of a virus in a cell by using a crosslinked product of PEGylated magnetic nanoparticles and catechol grafted poly-L-lysine by application of an external magnetic field. When the composition is used, a virus may be delivered into cells more rapidly and efficiently than in intracellular uptake of a virus by CAR-mediated endocytosis.