A pharmaceutical aerosol foam composition, comprising: an effective amount of a pharmaceutically active ingredient, wherein said pharmaceutically active ingredient is a vitamin or analogue thereof； an occlusive agent； an aqueous solvent； an organic cosolvent； wherein the pharmaceutically active ingredient is insoluble in both water and the occlusive agent； and the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use. hi a second embodiment, an oil-in water emulsion having a vitamin, an occlusive agent； an aqueous solvent； and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.
