CONGREVE, MILES STUART,DAGOSTIN, CLAUDIO,LAGU, BHARAT,BESONG, GILBERT,BRAIN, CHRISTOPHER THOMAS,BROOKS, CLINTON A.,HE, GUO,HOU, YING,HOWARD, STEVEN,LI, YUE,LU, YIPIN,MORTENSON, PAUL,SMITH, TROY,SUNG,
申请号:
DK09782051
公开号:
DK2331547T3
申请日:
2009.08.20
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.