BRAIN CHRISTOPHER THOMAS,BROOKS CLINTON A.,CONGREVE MILES STURAT,DAGOSTIN CLAUSIO,HE GUO,HOU YING,HOWARD STEVEN,LI YUE,LU YIPIN,MORTENSON PAUL,SMITH TROY,SUNG MOO,WOODHEAD STEVEN,WRONA WOJCIECH,BESONG
申请号:
TN2011000062
公开号:
TN2011000062A1
申请日:
2011.02.04
申请国别(地区):
TN
年份:
2012
代理人:
摘要:
The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.