Gilbert Besong,Christopher Thomas Brain,Clinton A. Brooks,Miles Stuart Congreve,Claudio Dagostin,Guo He,Ying Hou,Steven Howard,Yue Li,Yipin Lu,Paul Mortenson,Troy Smith,Moo Je Sung,Steven Woodhead,Woj
申请号：
US15886014
公开号：
US20180155351A1
申请日:
2018.02.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.
