Howard Allen Ketelson,James W. Davis,David L. Meadows
申请号：
US13302439
公开号：
US20120070402A1
申请日:
2011.11.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations.
