Howard Allen Ketelson,David L. Meadows,James W. Davis
申请号：
US14180396
公开号：
US09259472B2
申请日:
2014.02.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations.
