Ron Weiss,Maria Hottelet Foley,Jin Huh,Ross D. Jones
申请号：
US16741827
公开号：
US20200291428A1
申请日:
2020.01.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are engineered HSV-1 vectors comprising a modified HSV-1 genome. The engineered HSV-1 vectors can be used to deliver genetic circuits (e.g., up to 100 kb) to cells in vitro or in vivo. Methods of treating or diagnosing a disease (e.g., cancer) using the engineered HSV-1 vectors described herein are also provided.
