Paul Parren;Frank Beurskens;Rob N. De Jong;Aran Frank Labrijn;Janine Schuurman
发明人:
Paul Parren,Frank Beurskens,Rob N. De Jong,Aran Frank Labrijn,Janine Schuurman
申请号：
US14130543
公开号：
US10759867B2
申请日:
2012.07.06
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Described herein are polypeptides and related antibodies comprising a variant Fc domain. The variant Fc domain provide for stabilized Fc:Fc interactions when the polypeptide(s), antibody or antibodies are bound to its target, antigen or antigens on the surface of a cell, thus providing for improved effector functions, such as CDC-response.
