Parren, Paul,Beurskens, Frank,De Jong, Rob N.,Labrijn, Aran Frank,Schuurman, Janine
申请号：
AU2012280222
公开号：
AU2012280222A1
申请日:
2012.07.06
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
Described herein are polypeptides and related antibodies comprising a variant Fc domain. The variant Fc domain provide for stabilized Fc: Fc interactions when the polypeptide(s), antibody or antibodies are bound to its target, antigen or antigens on the surface of a cell, thus providing for improved effector functions, such as CDC- response.
