PARREN PAUL,BEURSKENS FRANK,DE JONG ROB N.,LABRIJN ARAN FRANK,SCHUURMAN JANINE
申请号:
IN807CHN2014
公开号:
IN807CHN2014A
申请日:
2014.01.31
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
Described herein are polypeptides and related antibodies comprising a variant Fc domain. The variant Fc domain provide for stabilized Fc: Fc interactions when the polypeptide(s) antibody or antibodies are bound to its target antigen or antigens on the surface of a cell thus providing for improved effector functions such as CDC response.