CARROLL, FRANK IVY,KORMOS, CHAD M.,ONDACHI, PAULINE W.,RUNYON, SCOTT P.,NAVARRO, HERNAN A.,THOMAS, JAMES B.,MASCARELLA, S. WAYNE
申请号：
CA3032046
公开号：
CA3032046A1
申请日:
2017.09.15
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Potent opioid receptor antagonists of formula (I) and their use as pharmacotherapies for treating depression, anxiety, schizophrenia, eating disorders, and addiction to cocaine, methamphetamine, nicotine, alcohol, and opiates are disclosed. More specifically, the disclosure provides potent and selective kappa opioid receptor antagonist compounds, pharmaceutical compositions of those compounds and uses of those compounds to ameliorate or treat addictions, eating disorders, etc.
