#$%^&*AU2019216588A120200305.pdf#####ABSTRACT An integrated guidewire includes a wire and an optical fiber. The wire is sized and shaped to move in an anatomical material transportation system of a patient. The optical fiber 5 has proximal and distal ends, the proximal-end is coupled to a device external to the patient, the optical fiber is configured to transfer optical signals between the distal-end and the device, and the wire and the optical fiber are intertwined with respect to one another.C) LCY) LO) C) Y C YJ