ANHYDROUS POLYMORPHS OF (2R,3S,4R,5R)-5-(6-(CYCLOPENTYLAMINO)-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL) } METHYL NITRATE AND PROCESSES OF PREPARATION THEREOF

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专利权人:

INOTEK PHARMACEUTICALS CORPORATION

发明人:

MCVICAR, WILLIAM, K.

申请号：

RSP20170796

公开号：

RS56150B1

申请日:

2013.01.25

申请国别(地区):

RS

年份:

2017

代理人:

摘要：

The present invention provides a novel anhydrous polymorph form of [(2R,3S,4R,5R) -5-(6-(cyc]opentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)]methyl nitrate (Compound A). The present invention also provides processes for preparation of the anhydrous polymorphic form of compound A, compositions containing the polymorph form, and use of the polymorph form for the preparation of ophthalmic compositions.

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中国工程科技知识中心

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