ANHYDROUS POLYMORPHS OF (2R,3S,4R,5R)-5-(6-(CYCLOPENTYLAMINO)-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL) } METHYL NITRATE AND PROCESSES OF PREPARATION THEREOF

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专利权人:

INOTEK PHARMACEUTICALS CORPORATION

发明人:

MCVICAR, WILLIAM, K.

申请号：

SG11201403979T

公开号：

SG11201403979TA

申请日:

2013.01.25

申请国别(地区):

SG

年份:

2014

代理人:

摘要：

The present invention provides a novel anhydrous polymorph form of [(2R,3S,4R,5R) -5-(6-(cyc]opentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)]methyl nitrate (Compound A). The present invention also provides processes for preparation of the anhydrous polymorphic form of compound A, compositions containing the polymorph form, and use of the polymorph form for the preparation of ophthalmic compositions.

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