PROCEDES AMELIORES POUR L'INACTIVATION D'ENTEROVIRUS ET L'ABSORPTION D'ADJUVANT ET COMPOSITIONS DE VACCIN A DOSES REDUITES OBTENUES AU MOYEN DE CES PROCEDES

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专利权人:

SERUM INSTITUTE OF INDIA PRIVATE LIMITED

发明人:

DHERE, RAJEEV MHALASAKANT,PISAL, SAMBHAJI SHANKAR,ZADE, JAGDISH KAMALAJI,SABALE, RAJENDRA NARAYAN

申请号：

CA2963897

公开号：

CA2963897A1

申请日:

2015.10.06

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention is directed to improved methods of Enterovirus inactivation by formaldehyde in presence of tromethamine buffer resulting in maximum recovery of D-antigen. Subsequent adsorption of said sIPV on aluminium hydroxide provides significantly dose reduced sIPV compositions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/