Improved methods for Enterovirus inactivation, adjuvant adsorption and dose reduced vaccine compositions obtained thereof

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专利权人:

Serum Institute of India Private Limited

发明人:

Dhere, Rajeev Mhalasakant,Pisal, Sambhaji Shankar,Zade, Jagdish Kamalaji,Sabale, Rajendra Narayan

申请号：

AU2015334495

公开号：

AU2015334495A1

申请日:

2015.10.06

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention is directed to improved methods of Enterovirus inactivation by formaldehyde in presence of tromethamine buffer resulting in maximum recovery of D-antigen. Subsequent adsorption of said sIPV on aluminium hydroxide provides significantly dose reduced sIPV compositions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/