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Methods for enterovirus inactivation, adjuvant adsorption and dose reduced vaccine compositions obtained thereof
专利权人:
SERUM INSTITUTE OF INDIA PRIVATE LIMITED
发明人:
Rajeev Mhalasakant Dhere,Sambhaji Shankar Pisal,Jagdish Kamalaji Zade,Rajendra Narayan Sabale
申请号:
US15517225
公开号:
US10485862B2
申请日:
2015.10.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention is directed to improved methods of Enterovirus inactivation by formaldehyde in presence of tromethamine buffer resulting in maximum recovery of D-antigen. Subsequent adsorption of said sIPV on aluminium hydroxide provides significantly dose reduced sIPV compositions.
来源网站:
中国工程科技知识中心
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