TAM TIM FAT,N ZEMBA BLAISE,LEUNG TOUNG REGIS,WANG YINGSHENG,ZHAO YANQING,YU LILY
申请号：
IN1393/MUMNP/2013
公开号：
IN2013MN01393A
申请日:
2013.07.17
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
A process for making pure crystalline D-isoglutamyl-D-tryptophan is provided which includes the step of deprotecting essentially pure N-tert-butoxycarbonyl-D-isoglutamyl-D-tryptophan or its diester to yield essentially pure D-isoglutamyl-D-tryptophan. A process is also provided for the preparation of pure mono ammonium salt of D-isoglutamyl-D-tryptophan from essentially pure N-tert-butoxycarbonyl-D-isoglutamyl-D-tryptophan. D-isoglutamyl-D-tryptophan, ammonium salt (1:1) is a stable pharmaceutical solid.
