Tam, Tim Fat,Yu, Lily,Wang, Yingsheng,N'zemba, Blaise,Zhao, Yanqing,Leung-Toung, Regis,Nzemba, Blaise
申请号：
AU2007327344
公开号：
AU2007327344B2
申请日:
2007.11.26
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
A process for making pure crystalline D-isoglutamyl-D-tryptophan is provided which includes the step of deprotecting essentially pure N-tert-butoxycarbonyl-D- isoglutamyl-D-tryptophan or its diester to yield essentially pure D-isoglutamyl-D- tryptophan. A process is also provided for the preparation of pure mono ammonium salt of D-isoglutamyl-D-tryptophan from essentially pure N-tert-butoxycarbonyl-D- isoglutamyl-D-tryptophan. D-isoglutamyl-D-tryptophan, ammonium salt (1 :1) is a stable pharmaceutical solid.
