Composition for treatment or prevention of vascular permeability disease comprising imatinib or a pharmaceutically acceptable salt thereof as an active ingredient
The present invention relates to a pharmaceutical composition for treating or preventing vascular permeability disease, which contains imatinib or a pharmaceutically acceptable salt thereof, which has been used as a therapeutic agent for chronic myelogenous leukemia, as an active ingredient, and the aforementioned composition. The present invention relates to a method for treating vascular permeability disease using the method. The pharmaceutical composition for treatment or prevention of vascular permeability disease of the present invention contains imatinib, which has been used as a therapeutic agent for conventional chronic myeloid leukemia, as an active ingredient, and provides a new use of imatinib, Since the vascular permeability disease can be effectively treated or prevented, it can be widely used for developing a therapeutic agent for a new vascular permeability related disease. [Selection] Figure 1本発明は、従来に慢性骨髄性白血病の治療剤として使用されていたイマチニブまたはこの薬学的に許容される塩を有効成分として含む血管透過性疾患の治療若しくは予防用薬学組成物及び前記組成物を用いて血管透過性疾患を治療する方法に関する。本発明の血管透過性疾患の治療若しくは予防用薬学組成物は、従来の慢性骨髄性白血病の治療剤として使用されていたイマチニブを有効成分として含み、イマチニブの新たな用途を提供するだけでなく、血管透過性疾患を効果的に治療若しくは予防できるので、新たな血管透過性関連疾患の治療剤開発に広く活用されることができるであろう。【選択図】 図1